Andrew Paterson
Scott Angle
Peng Chee
Robert Wright
Norma Trolinder
Donald Jones



Cotton, Inc.

Plant Genome Mapping Laboratory at the University of Georgia

The Consortium for Plant Biotechnology Research, Inc.

The Georgia Agribusiness Council

The Georgia Research Alliance, Inc.

The Georgia Traditional Industries Program

The OneGeorgia Authority

IIP-091856, Scaling a new adaptive peak for cotton.

The intellectual merit of the proposed activity

Toward a vision of US leadership for a global transition to bio-based products, we propose the development and implementation of genomic enabling tools needed to reinvigorate the infusion of genetic diversity into the cotton gene pool, providing environmentally benign solutions to the needs of producers, processors, and consumers. Cotton genome sequencing is proceeding rapidly, and the rationale for the proposed project is that the greatest challenge facing the cotton community is the conversion of sequence to knowledge. While the functions of perhaps half of the cotton genes can be deduced from comparison to botanical models, the greater complexity of the cotton genome than those of botanical models will require much new investment to realize the potential benefits of its sequencing. Creation of key enabling resources that can most efficiently be produced in the public domain is the focal point of our proposal. These resources will enable innovation by permitting researchers to identify specific genes that are likely to account for important features of the cotton plant, providing information needed by private partners to prioritize investments in development of value-added products. A distinguishing feature is our intellectual property plan, providing for the reservation of intellectual property rights that encourage investment while also tapping the creativity of public researchers as a 'virtual research and development network' for businesses that lack the critical mass to accomplish this goal alone.

The broader impacts resulting from the proposed activity

The state of Georgia recognized about two decades ago that success of businesses and industries demanded close ties between basic research and commercialization, and has positioned itself well to nurture new ventures spawned by basic research findings through the various stages of commercialization. Our network of partners will be key to sustained transformation of enabling resources into economic benefits. This transformation is expected to happen by at least three avenues: (1) New ventures to add value to bio-based products, expanding and diversifying regional entrepreneurial opportunities; (2) Empowering businesses by partnering with public researchers as a 'virtual R&D resource' to identify and capture value, and (3) Elevating the level and quality of science that can be done in cotton, as a result of strengthening public-sector research capacity. To more fully meet the broad workforce needs of the national innovation enterprise, we will partner with effective outreach networks such as 4-H and FFA to nurture the career development of 'home-grown' professionals with the training needed to exploit these tools, while preserving the links of these individuals to rural communities that have long been victims of "brain drain." The proposed activities are closely-tied to strong training and outreach programs with a successful history of engaging groups under-represented in the sciences, and which benefit from major commitments at the institutional and state level.




 · Objectives




Gene correspondence in fully-sequenced botanical models

Cotton QTL meta-analysis

Transposon stocks

Near-isogenic lines

Intellectual property policy